Luteolin是可能的Furin抑制剂

ychen
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Luteolin是可能的Furin抑制剂

ychen » 周三 10月 07, 2020 11:27 pm

Chinese herbal derived luteolin is suggested to be putative Furin inhibitor, with previous success against Dengue Fever. 

转https://doi.org/10.1016/j.obmed.2020.100281
A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection.
AbdelMassih AF, Ye J, Kamel A, Mishriky F, Ismail HA, Ragab HA, El Qadi L, Malak L, Abdu M, El-Husseiny M, Ashraf M, Hafez N, AlShehry N, El-Husseiny N, AbdelRaouf N, Shebl N, Hafez N, Youssef N, Afdal P, [...] Fouda R
Obes Med, 19:100281, 14 Jul 2020

https://doi.org/10.1016/j.antiviral.2017.03.026
Luteolin restricts dengue virus replication through inhibition of the proprotein convertase furin.
Peng M, Watanabe S, Chan KWK, He Q, Zhao Y, Zhang Z, Lai X, Luo D, Vasudevan SG, Li G
Antiviral Res, 143:176-185, 04 Apr 2017